Evaluating respiratory viral infections in children who have received transplants
Multi-center Evaluation of the Threat of Established and Emerging Respiratory Viral Infections in Pediatric Transplant Recipients
This study is looking at how respiratory viruses impact kids who have had organ or blood transplants, and it aims to find ways to predict and manage severe illness by analyzing samples from 2,000 young transplant patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Arkansas Children's Hospital Res Inst NIH-funded |
| Lab location | 1 site (Little Rock, United States) |
| Project ID | NIH-10907535 on NIH RePORTER |
What this research studies
This research investigates how respiratory viral infections affect children who have undergone hematopoietic cell or solid organ transplantation. It aims to develop a predictive model that combines viral load, viral sequencing, and immune responses to better understand the risk of severe disease progression. By collecting blood and nasal samples from 2000 pediatric transplant recipients, the study seeks to identify key indicators that could help in diagnosing and managing these infections more effectively. The research is conducted across multiple centers, leveraging a nationwide network dedicated to pediatric transplant infectious diseases.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years who have received hematopoietic cell or solid organ transplants.
Not a fit: Patients who are not pediatric transplant recipients or those outside the age range of 0-11 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools and treatment strategies for pediatric transplant recipients at risk of severe respiratory viral infections.
How similar studies have performed: This research builds on previous studies that have explored respiratory viral infections in transplant populations, but it aims to introduce novel predictive tools that have not been extensively tested.
Where this research is happening
Little Rock, United States
- Arkansas Children's Hospital Res Inst — Little Rock, United States (Active)
Researchers
- Principal investigator: Steinbach, William J — Arkansas Children's Hospital Res Inst
- Study coordinator: Steinbach, William J
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.