NIH-funded research NIH-funded research

Evaluating new tobacco products for safety and appeal

Official title: Product Evaluation and Manipulation Core (PEMC)

Funded at Ohio State University · NIH-10929388 · Data updated 2026-11-12

This study is looking at how different types of nicotine in tobacco products affect how much people like them, how addictive they are, and how harmful they can be, with the goal of finding safer options for current smokers and making sure new products aren't attractive to young people or non-smokers.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionOhio State University
NIH-funded
Lab location1 site (Columbus, UNITED STATES)
Project startSeptember 14, 2023
Project endAugust 31, 2028
Funding year2024
Award (this year)$505,530
NIH project number5U54CA287392-02
Project IDNIH-10929388 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include current smokers or users of smokeless tobacco products who are seeking safer alternatives.

Less likely to help

Patients who have never used tobacco products or are not interested in tobacco harm reduction may not benefit from this research.

What this research studies

This research focuses on understanding how different characteristics of nicotine in tobacco products, such as concentration and form, influence their appeal, addictiveness, and toxicity. By conducting human research and pilot studies, the project aims to fill existing data gaps regarding these products, especially concerning their potential for harm reduction among current smokers. The findings will help inform regulatory policies to ensure that new tobacco products are less appealing to youth and non-smokers while providing safer alternatives for established users.

Why it matters

Potential benefit: If successful, this research could lead to safer tobacco products that reduce health risks for current smokers.

How similar studies have gone: Previous research has shown promise in evaluating tobacco products for harm reduction, indicating that this approach could yield valuable insights.

Where this research is happening

  • Ohio State University
    Columbus, United States
    Active

Researchers

  • Principal investigator: El Hellani, Ahmad — Ohio State University
  • Study coordinator: El Hellani, Ahmad

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.