Evaluating new genomic tests for disease management and screening

BUILDING THE EVIDENCE BASE FOR APPROPRIATE AND EFFICIENT IMPLEMENTATION OF EMERGING GENOMIC TESTS FOR DISEASE MANAGEMENT AND SCREENING

NIH-funded research University of California, San Francisco · NIH-11078714

This study is looking at new genetic tests that can help catch diseases early and improve treatment, and it wants to find out how insurance companies decide if they will cover these tests so that more patients can benefit from them.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco NIH-funded
Lab location1 site (San Francisco, United States)
Project IDNIH-11078714 on NIH RePORTER

What this research studies

This research investigates the implementation of emerging genomic tests, specifically cell-free DNA tests and polygenic risk scores, to improve disease management and early detection. It aims to understand how insurance payers decide on coverage for these tests and assess their economic value from a patient-centered perspective. The study will involve systematic reviews of payer policies and interviews with payers to gather insights on evidence requirements. By addressing these factors, the research seeks to enhance patient access to potentially life-saving genomic testing.

Who could benefit from this research

Good fit: Ideal candidates for this research include patients at risk for atherosclerotic coronary disease and cancers who may benefit from genomic testing for early detection.

Not a fit: Patients who do not have a risk for the targeted conditions or those who are already symptomatic may not receive benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved access to genomic tests that enhance early detection and management of diseases, ultimately benefiting patient outcomes.

How similar studies have performed: Other research has shown success in evaluating genomic tests for clinical use, indicating that this approach is both relevant and necessary.

Where this research is happening

San Francisco, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions atherosclerotic coronary diseaseCancerscoronary arterial disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.