Evaluating new cancer treatments using advanced 3D models
Pre-Clinical Evaluation Core
This study is looking at how different types of cancer, like breast and prostate cancer, grow and behave in a lab setting that closely resembles the human body, so that researchers can find better treatments and understand how well they might work for patients.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Louisiana State Univ A&m Col Baton Rouge NIH-funded |
| Lab location | 1 site (Baton Rouge, United States) |
| Project ID | NIH-11062482 on NIH RePORTER |
What this research studies
This research focuses on understanding human cancer mechanisms by using advanced 3D tumor models that mimic the tumor microenvironment. The project involves promising junior investigators who are exploring various types of cancer, including osteosarcoma, breast cancer, liver cancer, and prostate cancer. By utilizing specialized mouse models and 3D tumor spheroids, the research aims to identify effective therapeutic strategies and improve predictions of treatment outcomes. The establishment of a Pre-Clinical Evaluation Core will provide essential support and expertise for these investigations.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with osteosarcoma, breast cancer, liver cancer, or prostate cancer who are seeking new treatment options.
Not a fit: Patients with cancers not included in the focus areas of this research may not receive any benefit.
Why it matters
Potential benefit: If successful, this research could lead to more effective cancer treatments tailored to individual patient needs.
How similar studies have performed: Previous research using 3D tumor models has shown promise in improving cancer treatment outcomes, indicating a potential for success in this approach.
Where this research is happening
Baton Rouge, United States
- Louisiana State Univ A&m Col Baton Rouge — Baton Rouge, United States (Active)
Researchers
- Principal investigator: Lopez, Mandi J. — Louisiana State Univ A&m Col Baton Rouge
- Study coordinator: Lopez, Mandi J.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.