Evaluating new blood tests for detecting multiple types of cancer.
Official title: Vanguard Study Administrative Supplement
Funded at Kaiser Foundation Research Institute · NIH-11262720 · Data updated 2026-11-12
This study is looking at how well a new blood test can find multiple types of cancer at once, especially for those cancers that don’t have good screening options yet, and it aims to include a variety of people to make sure the results are helpful for everyone.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kaiser Foundation Research Institute NIH-funded |
| Lab location | 1 site (Oakland, UNITED STATES) |
| Project start | March 7, 2025 |
| Project end | December 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $581,000 |
| NIH project number | 3UG1CA287011-02S1 |
| Project ID | NIH-11262720 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation are adults aged 45-75, particularly those from underrepresented racial and ethnic groups.
✕Less likely to help
Patients outside the age range of 45-75 or those not belonging to the targeted demographic groups may not benefit from this research.
What this research studies
This research investigates the feasibility and effectiveness of multi-cancer detection (MCD) tests that analyze cell-free DNA from a single blood draw. The study aims to assess how well these tests can be integrated into cancer screening practices, especially for cancers that currently lack effective screening methods. It focuses on engaging diverse populations, particularly underserved groups, to ensure broad applicability of the findings. Participants will be recruited from a large healthcare system, allowing for a comprehensive evaluation of the tests across different demographics.
Why it matters
Potential benefit: If successful, this research could lead to improved cancer screening methods that are more accessible and effective for diverse populations.
How similar studies have gone: Previous research has shown promise in using similar blood-based tests for cancer detection, indicating a potential for success in this novel approach.
Where this research is happening
-
Kaiser Foundation Research Institute
Oakland, United States Active
Researchers
- Principal investigator: Lee, Jeffrey Kuang Zou — Kaiser Foundation Research Institute
- Study coordinator: Lee, Jeffrey Kuang Zou
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.