Evaluating lung cancer screening benefits and risks for Veterans
Official title: Lung cancer screening for Veterans: measuring real-world benefit and harms
Funded at Veterans Affairs Med Ctr San Francisco · NIH-10921371 · Data updated 2026-11-12
This study is looking at how well lung cancer screening works for Veterans, who may have different health challenges than those in earlier studies, to help figure out which Veterans might benefit the most from screening.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterans Affairs Med Ctr San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | October 1, 2024 |
| Project end | September 30, 2029 |
| Funding year | 2025 |
| NIH project number | 1IK2CX002713-01A1 |
| Project ID | NIH-10921371 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are Veterans who are eligible for lung cancer screening and may have varying levels of health and comorbidities.
✕Less likely to help
Patients who are not Veterans or those who do not meet the eligibility criteria for lung cancer screening may not benefit from this research.
What this research studies
This research investigates the real-world effectiveness and potential harms of lung cancer screening (LCS) specifically for Veterans, who often have multiple health issues compared to participants in previous trials. The study aims to create two cohorts to assess how well LCS works in the VA system and to identify health metrics that can predict which Veterans will benefit from screening. By analyzing data from these cohorts, the research seeks to provide tailored recommendations for lung cancer screening based on individual health status.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer lung cancer screening practices for Veterans, ultimately improving patient outcomes.
How similar studies have gone: Previous trials have shown that lung cancer screening can prevent lung cancer deaths, but this research aims to explore its effectiveness in a more diverse and health-compromised population, making it a novel approach.
Where this research is happening
-
Veterans Affairs Med Ctr San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Rustagi, Alison Silvis — Veterans Affairs Med Ctr San Francisco
- Study coordinator: Rustagi, Alison Silvis
Related research
Other NIH-funded projects on the same topics.
-
Digital health strategies to expand lung cancer screening in safety-net clinics
A funded project aims to help low-resource clinics increase the use of lung cancer screening for patients who smoke or are at risk.
-
Integrated approach to lung screening and quitting for African Americans
A multi-level program aims to boost LDCT lung cancer screening uptake and help African American smokers quit, with support from a comprehensive community-focused plan.
-
Population health approach to boost lung cancer screening at community clinics
A large Utah project aims to help community clinics reach more eligible adults to get low-dose CT lung cancer screening.
-
Group-based tobacco treatment for older adults after lung cancer screening
A study tests a group-based tobacco cessation program for older adults who are getting lung cancer screening to help them quit smoking.
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Personalized Lung Cancer Screening for Veterans
Aimed at improving who gets screened and how lung cancer is diagnosed among Veterans using personalized tools.
-
Proteogenomic framework to improve lung cancer screening with biomarkers
A biomarker-based approach aims to refine LDCT lung cancer screening so more cancers are caught early while reducing unnecessary procedures.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.