Evaluating kidney blood vessels in a genetic kidney disease
Noninvasive evaluation of the intrarenal microvasculature in ADPKD
This study is looking at a new, gentle way to see how small blood vessels in the kidneys change in people with Autosomal Dominant Polycystic Kidney Disease (ADPKD), which could help doctors better understand and treat the condition.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mayo Clinic Rochester NIH-funded |
| Lab location | 1 site (Rochester, United States) |
| Project ID | NIH-10456178 on NIH RePORTER |
What this research studies
This research focuses on Autosomal Dominant Polycystic Kidney Disease (ADPKD), a condition that leads to kidney failure due to the growth of cysts. The study aims to develop a noninvasive method to assess the small blood vessels within the kidneys, which are crucial for understanding how the disease progresses. By utilizing advanced imaging techniques like super-resolution ultrasound, researchers hope to gain insights into the vascular changes that contribute to kidney damage. This approach could lead to better monitoring and treatment strategies for patients with ADPKD.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with Autosomal Dominant Polycystic Kidney Disease.
Not a fit: Patients without a diagnosis of ADPKD or those with advanced kidney failure may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a new way to monitor kidney health in ADPKD patients, potentially leading to improved treatment options.
How similar studies have performed: Previous studies using advanced imaging techniques have shown promise in assessing kidney conditions, suggesting that this approach may yield valuable insights.
Where this research is happening
Rochester, United States
- Mayo Clinic Rochester — Rochester, United States (Active)
Researchers
- Principal investigator: Irazabal, Maria V — Mayo Clinic Rochester
- Study coordinator: Irazabal, Maria V
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.