Evaluating hybrid closed loop therapy for underserved adults with type 1 diabetes

Effectiveness Trial to Support Adoption of Hybrid Closed Loop Therapy in Underserved Adults with Type 1 Diabetes: Impact of System Functionality and Features on Lived Experience

NIH-funded research Boston Medical Center · NIH-11005063

This study is looking at how well different types of hybrid closed loop therapy can help adults with type 1 diabetes from underserved communities manage their diabetes and improve their health over nine months.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionBoston Medical Center NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11005063 on NIH RePORTER

What this research studies

This research investigates the effectiveness of hybrid closed loop (HCL) therapy in adults with type 1 diabetes (T1D) from underserved communities. It aims to assess how different HCL systems, which vary in automation and user input, impact diabetes management and overall health outcomes. The study will include a randomized trial with broader eligibility criteria and a longer follow-up period to better understand the benefits and risks of HCL therapy in this population. Participants will be monitored for key health metrics, including blood sugar levels and weight changes, over a nine-month period.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults with type 1 diabetes, particularly those from underserved communities who may have higher A1c levels and face challenges in diabetes management.

Not a fit: Patients who do not have type 1 diabetes or those who are not part of underserved communities may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diabetes management and health outcomes for underserved adults with type 1 diabetes.

How similar studies have performed: Previous research has shown that hybrid closed loop therapy can be effective in more advantaged populations, but this study aims to explore its applicability in underserved groups, making it a novel approach.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.