Evaluating hybrid closed loop therapy for underserved adults with type 1 diabetes
Official title: Effectiveness Trial to Support Adoption of Hybrid Closed Loop Therapy in Underserved Adults with Type 1 Diabetes: Impact of System Functionality and Features on Lived Experience
Funded at Boston Medical Center · NIH-11005063 · Data updated 2026-11-12
This study is looking at how well different types of hybrid closed loop therapy can help adults with type 1 diabetes from underserved communities manage their diabetes and improve their health over nine months.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | January 1, 2024 |
| Project end | December 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $854,975 |
| NIH project number | 5R01DK138309-02 |
| Project ID | NIH-11005063 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults with type 1 diabetes, particularly those from underserved communities who may have higher A1c levels and face challenges in diabetes management.
✕Less likely to help
Patients who do not have type 1 diabetes or those who are not part of underserved communities may not benefit from this research.
What this research studies
This research investigates the effectiveness of hybrid closed loop (HCL) therapy in adults with type 1 diabetes (T1D) from underserved communities. It aims to assess how different HCL systems, which vary in automation and user input, impact diabetes management and overall health outcomes. The study will include a randomized trial with broader eligibility criteria and a longer follow-up period to better understand the benefits and risks of HCL therapy in this population. Participants will be monitored for key health metrics, including blood sugar levels and weight changes, over a nine-month period.
Why it matters
Potential benefit: If successful, this research could lead to improved diabetes management and health outcomes for underserved adults with type 1 diabetes.
How similar studies have gone: Previous research has shown that hybrid closed loop therapy can be effective in more advantaged populations, but this study aims to explore its applicability in underserved groups, making it a novel approach.
Where this research is happening
-
Boston Medical Center
Boston, United States Active
Researchers
- Principal investigator: Wolpert, Howard a — Boston Medical Center
- Study coordinator: Wolpert, Howard a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.