NIH-funded research U01 cooperative agreement

Evaluating how well respiratory virus vaccines work in a diverse healthcare system

Official title: RFA-IP-22-004, Evaluating respiratory virus vaccine effectiveness in a large, diverse healthcare system

Funded at University of Pittsburgh at Pittsburgh · NIH-10703261 · Data updated 2026-11-12

This study is looking at how well vaccines for respiratory viruses like the flu and COVID-19 work for people of all ages, and it’s for anyone who wants to know more about vaccine protection during the cold and flu season.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh
NIH-funded
Lab location1 site (Pittsburgh, United States)
Project startSeptember 30, 2022
Project endSeptember 30, 2027
Funding year2023
Award (this year)$1,900,000
NIH project number5U01IP001184-02
Project IDNIH-10703261 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation include outpatients aged 6 months and older who are receiving care at UPMC or federally qualified health centers during the respiratory season.

Less likely to help

Patients who are not receiving care at the participating healthcare centers or those who do not fall within the specified age groups may not benefit from this research.

What this research studies

This research investigates the effectiveness of vaccines against respiratory viruses, including influenza and COVID-19, within a large and diverse healthcare system. By enrolling outpatients during the respiratory season and conducting follow-up surveys, the study aims to gather data on vaccine effectiveness across different age groups. The research will also include genetic sequencing of selected specimens to track viral trends. This comprehensive approach will help understand how well vaccines protect against these viruses over time.

Why it matters

Potential benefit: If successful, this research could lead to improved vaccine strategies and better protection against respiratory viruses for patients.

How similar studies have gone: Previous research has shown success in evaluating vaccine effectiveness using similar methodologies, indicating that this approach is both tested and reliable.

Where this research is happening

  • University of Pittsburgh at Pittsburgh
    Pittsburgh, United States
    Active

Researchers

  • Principal investigator: Zimmerman, Richard K — University of Pittsburgh at Pittsburgh
  • Study coordinator: Zimmerman, Richard K

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.