Evaluating how well respiratory virus vaccines work in a diverse healthcare system

RFA-IP-22-004, Evaluating respiratory virus vaccine effectiveness in a large, diverse healthcare system

NIH-funded research University of Pittsburgh at Pittsburgh · NIH-10703261

This study is looking at how well vaccines for respiratory viruses like the flu and COVID-19 work for people of all ages, and it’s for anyone who wants to know more about vaccine protection during the cold and flu season.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionUniversity of Pittsburgh at Pittsburgh NIH-funded
Lab location1 site (Pittsburgh, United States)
Project IDNIH-10703261 on NIH RePORTER

What this research studies

This research investigates the effectiveness of vaccines against respiratory viruses, including influenza and COVID-19, within a large and diverse healthcare system. By enrolling outpatients during the respiratory season and conducting follow-up surveys, the study aims to gather data on vaccine effectiveness across different age groups. The research will also include genetic sequencing of selected specimens to track viral trends. This comprehensive approach will help understand how well vaccines protect against these viruses over time.

Who could benefit from this research

Good fit: Ideal candidates for participation include outpatients aged 6 months and older who are receiving care at UPMC or federally qualified health centers during the respiratory season.

Not a fit: Patients who are not receiving care at the participating healthcare centers or those who do not fall within the specified age groups may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved vaccine strategies and better protection against respiratory viruses for patients.

How similar studies have performed: Previous research has shown success in evaluating vaccine effectiveness using similar methodologies, indicating that this approach is both tested and reliable.

Where this research is happening

Pittsburgh, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.