Evaluating heart function in adults with tetralogy of Fallot
Official title: High spatial resolution evaluation of subclinical regions of myocardial dysfunction in adult patients with tetralogy of Fallot
Funded at University of California, San Diego · NIH-11004602 · Data updated 2026-11-12
This study is looking at how well the hearts of adults who had surgery for tetralogy of Fallot are working, using a new type of CT scan to find any problems that regular tests might miss, so we can help improve their care and health in the long run.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2024 |
| Award (this year) | $41,969 |
| NIH project number | 5F31HL165881-02 |
| Project ID | NIH-11004602 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults who have had surgical repair for tetralogy of Fallot and are experiencing or at risk for heart dysfunction.
✕Less likely to help
Patients who have not undergone surgical repair for tetralogy of Fallot or those with other unrelated cardiac conditions may not benefit from this research.
What this research studies
This research focuses on understanding heart function in adults who have undergone surgical repair for tetralogy of Fallot, a congenital heart defect. It aims to develop a new imaging technique using computed tomography (CT) to identify areas of heart dysfunction that may not be visible with standard methods. By measuring regional heart performance, the study seeks to improve patient management and outcomes for those experiencing long-term complications. Patients will undergo advanced imaging to assess their heart's function and identify any early signs of dysfunction.
Why it matters
Potential benefit: If successful, this research could lead to better monitoring and management strategies for adults with tetralogy of Fallot, potentially reducing adverse cardiac events.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques to assess heart function, indicating that this approach may yield valuable insights.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Craine, Amanda — University of California, San Diego
- Study coordinator: Craine, Amanda
Related research
Other NIH-funded projects on the same topics.
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Why repaired Tetralogy of Fallot can cause heart rhythm problems and low exercise capacity
This project looks at whether rising pressure in the right atrium leads to arrhythmias and worse exercise ability in adults who had Tetralogy of Fallot repaired.
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Using beta-blockers to help heart cells grow in children with Tetralogy of Fallot
This study is looking at how a type of medicine called beta-blockers might help heart muscle cells grow in children with Tetralogy of Fallot, a heart condition they were born with, to better understand how to improve their heart function after surgery.
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Using AI to predict heart function in patients with repaired tetralogy of Fallot
This study is looking to make it easier for people who have had surgery for tetralogy of Fallot to understand their heart health by using advanced technology to analyze heart tests, so they can avoid extra MRIs and get better care.
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New MRI techniques to predict heart issues in patients with tetralogy of Fallot
This study is looking to help people who have had surgery for tetralogy of Fallot by using special heart scans to better predict serious heart problems, so doctors can know when to step in and provide the right care.
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Understanding heart issues in patients with repaired tetralogy of Fallot
This study is looking at why some people who have had surgery for tetralogy of Fallot experience heart rhythm problems and trouble with exercise, and it hopes to find out if fixing a specific heart valve early on can help them feel better and live longer.
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Understanding heart changes in children with Tetralogy of Fallot
This study looks at how the hearts of children with Tetralogy of Fallot change over time, especially the right ventricle, to help doctors find out which kids might need extra care after their surgery.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.