Evaluating gene expression tests for localized prostate cancer treatment decisions
Determining the clinical impact of gene expression testing in localized prostate cancer
This study is looking at how gene testing can help find the best treatment for men with localized prostate cancer, so they can avoid unnecessary treatments and get the right care based on their individual risk.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-10913497 on NIH RePORTER |
What this research studies
This research investigates how gene expression testing can help determine the best treatment options for men with localized prostate cancer. By analyzing tissue samples and combining genetic, clinical, and pathological data, the study aims to create a universal risk score that can guide treatment decisions. The goal is to reduce unnecessary treatments while ensuring that men with higher-risk cancer receive appropriate care. Patients will be followed in a statewide registry to validate the effectiveness of this approach.
Who could benefit from this research
Good fit: Ideal candidates for this research are men who have been newly diagnosed with localized prostate cancer.
Not a fit: Patients with advanced prostate cancer or those who have already undergone treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more personalized and effective treatment plans for men with localized prostate cancer, improving their quality of life.
How similar studies have performed: Previous research has shown promise in using gene expression tests for cancer treatment decisions, indicating that this approach could be beneficial.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Morgan, Todd M. — University of Michigan at Ann Arbor
- Study coordinator: Morgan, Todd M.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.