Evaluating depression treatment effectiveness in TB care in South Africa.

The Effectiveness and Cost-Effectiveness of Implementing Evidence-Based Depression Treatment within the TB Care Platform in South Africa: A Hybrid Effectiveness-Implementation Trial

NIH-funded research New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC · NIH-10582160

This study is looking at how well and affordably we can help people with both tuberculosis (TB) and depression by combining their treatments, so if you’re dealing with these conditions in South Africa, your experience could help improve care for others like you!

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNew York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10582160 on NIH RePORTER

What this research studies

This research investigates how effective and cost-efficient it is to implement evidence-based treatments for depression within the tuberculosis (TB) care framework in South Africa. The study will involve collecting primary data and using mixed-methods analysis to understand the integration of depression treatment with TB care. Patients will be monitored to assess the impact of these treatments on their mental health and overall well-being. The research aims to provide insights that could improve care for patients suffering from both TB and depression.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with tuberculosis who also experience symptoms of depression.

Not a fit: Patients who do not have tuberculosis or depression may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved mental health outcomes for patients with TB by integrating effective depression treatments into their care.

How similar studies have performed: Previous research has shown promising results in integrating mental health treatments within chronic disease care, suggesting potential success for this approach.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.