Evaluating community strategies to prevent substance use and overdose linked to childhood trauma.

RFA-CE-22-009 Rigorous Evaluation of Community-Level Substance Use and Overdose Prevention Frameworks that Incorporate ACEs-Related Prevention Strategies

NIH-funded research Research Triangle Institute · NIH-10835839

This study is looking at how community programs can help families affected by tough childhood experiences and substance use by providing support and resources, and it’s aimed at making a positive difference in 20 New Jersey communities that really need it.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionResearch Triangle Institute NIH-funded
Lab location1 site (Research Triangle Park, United States)
Project IDNIH-10835839 on NIH RePORTER

What this research studies

This research investigates how community-level interventions can help reduce substance use and overdose rates by addressing Adverse Childhood Experiences (ACEs). It focuses on integrating family support services with trauma-informed care to assist families in accessing necessary resources. The study will evaluate the effectiveness of these interventions across 20 communities in New Jersey that are heavily impacted by substance use and ACEs. By combining established programs with trained advocates, the research aims to create a comprehensive support system for affected families.

Who could benefit from this research

Good fit: Ideal candidates for this research are families in New Jersey who have experienced Adverse Childhood Experiences and are at risk for substance use issues.

Not a fit: Patients who do not reside in the targeted New Jersey communities or who have not experienced ACEs may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could significantly reduce substance use and overdose rates in communities affected by childhood trauma.

How similar studies have performed: Previous research has shown that community-level interventions can effectively reduce the impact of ACEs and substance use, indicating a promising approach for this study.

Where this research is happening

Research Triangle Park, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.