Evaluating cardiovascular risk using CT calcium score exams

Cardiovascular risk from comprehensive evaluation of the CT calcium score exam

NIH-funded research Case Western Reserve University · NIH-11045666

This study is looking at how computer technology can help doctors better understand heart health by analyzing CT scans, especially for people at higher risk of heart problems, like those in the African American community, so they can get more personalized care and treatment.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCase Western Reserve University NIH-funded
Lab location1 site (Cleveland, United States)
Project IDNIH-11045666 on NIH RePORTER

What this research studies

This research investigates how machine learning can analyze CT calcium score images to predict the risk of major cardiovascular events. By examining coronary artery calcifications and thoracic fat deposits, the study aims to improve the understanding of cardiometabolic diseases. Patients will benefit from more accurate risk assessments, which can guide personalized preventive therapies and enhance clinical decision-making. The research focuses on identifying high-risk individuals, particularly within the African American population, to improve adherence to treatment plans.

Who could benefit from this research

Good fit: Ideal candidates include individuals with a CT calcium score exam, particularly those from the African American population or those at risk for cardiovascular diseases.

Not a fit: Patients without a CT calcium score exam or those with no cardiovascular risk factors may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more precise cardiovascular risk assessments and tailored preventive therapies for patients.

How similar studies have performed: Previous research has shown promise in using machine learning for cardiovascular risk prediction, making this approach both innovative and building on existing knowledge.

Where this research is happening

Cleveland, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.