Evaluating blood biomarkers for predicting outcomes in mild traumatic brain injury
Analytical Validation of Tau and P-Tau as acute and subacute prognostic biomarkers for complicated mild TBI
This study is looking at two blood tests, Tau and phospho-Tau, to see if they can help doctors better predict how people with complicated mild traumatic brain injuries will recover, and by joining in, you could help improve care for others with similar injuries.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Morehouse School of Medicine NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10934383 on NIH RePORTER |
What this research studies
This research focuses on validating two promising blood biomarkers, Tau and phospho-Tau (P-Tau), to better predict outcomes for patients with complicated mild traumatic brain injury (TBI). The study aims to establish standardized testing methods and assess the performance of these biomarkers in identifying patients at risk for prolonged post-concussive symptoms. By analyzing blood samples from various adult age groups, the research seeks to fill existing gaps in TBI diagnostics and improve patient care. Participants may contribute to the development of more effective prognostic tools for TBI management.
Who could benefit from this research
Good fit: Ideal candidates for participation include adults aged 21 and older who have experienced a mild traumatic brain injury.
Not a fit: Patients with severe traumatic brain injuries or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnostic tools that help identify patients at risk for long-term complications following mild TBI.
How similar studies have performed: Previous research has shown promise in using blood biomarkers for TBI diagnosis, but the specific use of Tau and P-Tau as prognostic indicators is still being explored.
Where this research is happening
Atlanta, United States
- Morehouse School of Medicine — Atlanta, United States (Active)
Researchers
- Principal investigator: Wang, Kevin Ka Wang — Morehouse School of Medicine
- Study coordinator: Wang, Kevin Ka Wang
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.