Evaluating antiplatelet therapy options for older stroke patients
Antiplatelet in Stroke: Safety and Effectiveness in Seniors (ASSESS)
This study is looking at how to choose the best blood-thinning medications, like aspirin or clopidogrel, for older adults who have had a specific type of stroke, so we can create safer and more effective treatment plans just for them.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project ID | NIH-10657798 on NIH RePORTER |
What this research studies
This research investigates how to select the best antiplatelet medications, like aspirin or clopidogrel, for older patients who have experienced a noncardioembolic ischemic stroke. It aims to understand the unique characteristics of these patients, such as their age, sex, and existing health conditions, to tailor treatment plans that minimize risks and maximize benefits. By analyzing data from the American Heart Association's guidelines and Medicare claims, the study seeks to develop patient-centered strategies for better treatment decisions. The goal is to improve both primary and secondary prevention of strokes and cardiovascular diseases in older adults.
Who could benefit from this research
Good fit: Ideal candidates for this research are older adults who have had a noncardioembolic ischemic stroke and are considering antiplatelet therapy.
Not a fit: Patients who are not seniors or those who have not experienced a noncardioembolic ischemic stroke may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and safer antiplatelet therapy choices for older stroke patients, reducing their risk of recurrent strokes and complications.
How similar studies have performed: Previous research has shown that personalized treatment approaches can improve outcomes in cardiovascular care, suggesting potential success for this study's methodology.
Where this research is happening
Dallas, United States
- Ut Southwestern Medical Center — Dallas, United States (Active)
Researchers
- Principal investigator: Xian, Ying — Ut Southwestern Medical Center
- Study coordinator: Xian, Ying
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.