Evaluating and predicting risk for angle closure disease using advanced imaging techniques
Clinical Evaluation and Risk Stratification of Angle Closure Disease Using Quantitative OCT
['FUNDING_R01'] · UNIVERSITY OF SOUTHERN CALIFORNIA · NIH-11004976
This study is looking at a new way to spot and understand the risk of angle closure disease, which can lead to glaucoma and blindness, so that we can help people at risk get the care they need earlier and more effectively.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF SOUTHERN CALIFORNIA (nih funded) |
| Locations | 1 site (Los Angeles, UNITED STATES) |
| Trial ID | NIH-11004976 on ClinicalTrials.gov |
What this research studies
This research focuses on improving the detection and risk assessment of angle closure disease, a leading cause of glaucoma and irreversible blindness. By utilizing quantitative optical coherence tomography (OCT), the study aims to provide a more accurate and less subjective method for identifying patients at risk of developing primary angle closure glaucoma (PACG). The goal is to enhance early intervention strategies, particularly for vulnerable populations, thereby reducing the incidence of blindness associated with this condition.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with narrow angles or those identified as at risk for developing primary angle closure glaucoma, particularly within vulnerable racial groups.
Not a fit: Patients who do not have narrow angles or are not at risk for primary angle closure glaucoma may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better screening and treatment strategies for patients at risk of angle closure glaucoma, ultimately reducing blindness rates.
How similar studies have performed: Previous research has indicated that advanced imaging techniques like OCT can improve the detection of glaucoma-related conditions, suggesting a promising avenue for this approach.
Where this research is happening
Los Angeles, UNITED STATES
- UNIVERSITY OF SOUTHERN CALIFORNIA — Los Angeles, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: XU, BENJAMIN Y. — UNIVERSITY OF SOUTHERN CALIFORNIA
- Study coordinator: XU, BENJAMIN Y.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.