Evaluating and improving how penicillin allergies are assessed in outpatient settings

Adapting and Implementing Risk-Stratified Penicillin Allergy Evaluation in Key Outpatient Settings

NIH-funded research Vanderbilt University Medical Center · NIH-11023801

This study is looking to help patients with unverified penicillin allergies, especially those needing surgery or other treatments, by creating easy self-assessments to better understand their allergies and improve their access to effective antibiotics.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionVanderbilt University Medical Center NIH-funded
Lab location1 site (Nashville, United States)
Project IDNIH-11023801 on NIH RePORTER

What this research studies

This research focuses on addressing the issue of unverified penicillin allergy labels that affect many patients and limit their access to effective antibiotic treatments. The team aims to implement a risk-stratified approach to evaluate penicillin allergies in outpatient settings, particularly for surgical, transplant, and obstetric patients. By developing patient-centered self-assessments and measuring the effectiveness of these assessments, the research seeks to identify barriers and facilitators to better manage penicillin allergies. The ultimate goal is to improve antibiotic stewardship and patient outcomes by accurately identifying low-risk penicillin allergies.

Who could benefit from this research

Good fit: Ideal candidates for this research include patients with a history of penicillin allergy labels who are scheduled for outpatient surgical or obstetric procedures.

Not a fit: Patients who do not have a penicillin allergy label or those who have confirmed severe allergies to penicillin may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate identification of penicillin allergies, allowing patients to receive appropriate antibiotic treatments and reducing the risk of treatment failures.

How similar studies have performed: Previous research has shown success in implementing risk-stratified management for penicillin allergy delabeling, indicating that this approach has potential for further application in outpatient settings.

Where this research is happening

Nashville, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.