Evaluating and improving how penicillin allergies are assessed in outpatient settings
Official title: Adapting and Implementing Risk-Stratified Penicillin Allergy Evaluation in Key Outpatient Settings
Funded at Vanderbilt University Medical Center · NIH-11023801 · Data updated 2026-11-12
This study is looking to help patients with unverified penicillin allergies, especially those needing surgery or other treatments, by creating easy self-assessments to better understand their allergies and improve their access to effective antibiotics.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vanderbilt University Medical Center NIH-funded |
| Lab location | 1 site (Nashville, United States) |
| Project start | September 30, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $490,523 |
| NIH project number | 1R01HS030234-01 |
| Project ID | NIH-11023801 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include patients with a history of penicillin allergy labels who are scheduled for outpatient surgical or obstetric procedures.
✕Less likely to help
Patients who do not have a penicillin allergy label or those who have confirmed severe allergies to penicillin may not benefit from this research.
What this research studies
This research focuses on addressing the issue of unverified penicillin allergy labels that affect many patients and limit their access to effective antibiotic treatments. The team aims to implement a risk-stratified approach to evaluate penicillin allergies in outpatient settings, particularly for surgical, transplant, and obstetric patients. By developing patient-centered self-assessments and measuring the effectiveness of these assessments, the research seeks to identify barriers and facilitators to better manage penicillin allergies. The ultimate goal is to improve antibiotic stewardship and patient outcomes by accurately identifying low-risk penicillin allergies.
Why it matters
Potential benefit: If successful, this research could lead to more accurate identification of penicillin allergies, allowing patients to receive appropriate antibiotic treatments and reducing the risk of treatment failures.
How similar studies have gone: Previous research has shown success in implementing risk-stratified management for penicillin allergy delabeling, indicating that this approach has potential for further application in outpatient settings.
Where this research is happening
-
Vanderbilt University Medical Center
Nashville, United States Active
Researchers
- Principal investigator: Stone, Cosby a — Vanderbilt University Medical Center
- Study coordinator: Stone, Cosby a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.