Evaluating a treatment for veterans with obsessive-compulsive disorder
Official title: A Mixed-Methods Economic Evaluation of Exposure and Response Prevention in Veterans with Obsessive-Compulsive Disorder
Funded at Michael E Debakey VA Medical Center · NIH-10879793 · Data updated 2026-11-12
This study is looking at how well a therapy called Exposure and Response Prevention (ERP) works for veterans with obsessive-compulsive disorder (OCD) when delivered online, compared to a group that will receive Stress Management Training, to see which helps them feel better and function well in their daily lives.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Michael E Debakey VA Medical Center NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project start | June 1, 2022 |
| Project end | May 31, 2026 |
| Funding year | 2024 |
| NIH project number | 3I01RX003677-02S1 |
| Project ID | NIH-10879793 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are veterans diagnosed with obsessive-compulsive disorder who have not received adequate treatment.
✕Less likely to help
Patients who do not have obsessive-compulsive disorder or those who have already received effective treatment may not benefit from this research.
What this research studies
This research investigates the effectiveness of Exposure and Response Prevention (ERP), a behavioral therapy, for veterans suffering from obsessive-compulsive disorder (OCD). The study will compare telehealth-delivered ERP to a control group receiving Stress Management Training, aiming to assess improvements in functioning and the feasibility of implementing ERP within the Veterans Health Administration. By utilizing mixed-method economic evaluations, the research will also explore the trade-offs of different treatment strategies for OCD in veterans.
Why it matters
Potential benefit: If successful, this research could significantly improve treatment access and outcomes for veterans with obsessive-compulsive disorder.
How similar studies have gone: Previous research has shown promising results for telehealth interventions in mental health, suggesting potential success for this approach in treating OCD.
Where this research is happening
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Michael E Debakey VA Medical Center
Houston, United States Active
Researchers
- Principal investigator: Fletcher, Terri Lynn — Michael E Debakey VA Medical Center
- Study coordinator: Fletcher, Terri Lynn
Related research
Other NIH-funded projects on the same topics.
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Exposure and Response Prevention for Veterans with OCD (via video), to help daily functioning
A Veterans-focused program tests video-delivered ERP therapy to help people with OCD and sometimes PTSD feel more able to work and enjoy daily life.
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Understanding and improving fear and safety learning in OCD
A study at Yale will test brain-based methods to help adults with OCD improve safety learning and fear extinction during therapy.
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Understanding OCD: how people control distressing thoughts and urges
A research team is exploring how the brain and behavior work together in OCD to reduce distress and urge-driven actions.
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Neural training to improve stopping impulses in OCD and related conditions
A new computer-based training helps people with OCD, trichotillomania, or skin picking disorders improve their ability to stop automatic urges.
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How genes affect obsessive-compulsive disorder in people of Latin American ancestry
This project looks at how genetic differences influence OCD risk in people with Latin American ancestry.
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Pinpointing brain areas and cell types linked to OCD, Tourette, and anorexia with genetics
A short, patient-friendly project that looks at how genes are connected to OCD, Tourette syndrome, and anorexia nervosa to understand which brain regions and cells are involved.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.