Evaluating a new type of stent coating to improve artery healing
Dual action nanomatrix coated stent evaluation using engineered artery sheets with atherosclerotic features
['FUNDING_R01'] · UNIVERSITY OF ALABAMA AT BIRMINGHAM · NIH-11063841
This study is testing a new type of stent coating that helps arteries heal better after being treated for atherosclerosis, and it could lead to safer and more effective options for patients undergoing artery procedures.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF ALABAMA AT BIRMINGHAM (nih funded) |
| Locations | 1 site (BIRMINGHAM, UNITED STATES) |
| Trial ID | NIH-11063841 on ClinicalTrials.gov |
What this research studies
This research investigates a novel stent coating designed to enhance healing in arteries affected by atherosclerosis. The study focuses on developing a nanomatrix that releases nitric oxide to promote endothelial health and reduce adverse effects associated with traditional drug-eluting stents. By using engineered artery sheets that mimic atherosclerotic conditions, the research aims to better understand how this new coating performs compared to existing options. Patients may benefit from improved stent designs that minimize complications and enhance recovery after artery procedures.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with atherosclerotic cardiovascular disease who may require stent implantation.
Not a fit: Patients without atherosclerotic disease or those who do not require stent placement may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to stents that significantly reduce complications and improve healing in patients with narrowed arteries.
How similar studies have performed: While there have been advancements in stent technology, this specific approach using a nitric oxide-releasing nanomatrix is innovative and has not been widely tested in clinical settings.
Where this research is happening
BIRMINGHAM, UNITED STATES
- UNIVERSITY OF ALABAMA AT BIRMINGHAM — BIRMINGHAM, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: JUN, HO-WOOK — UNIVERSITY OF ALABAMA AT BIRMINGHAM
- Study coordinator: JUN, HO-WOOK
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.