Evaluating a new treatment for fetal kidney issues during pregnancy
Renal Anhydramnios Fetal Therapy (RAFT) Trial
This study is looking at a new treatment called serial amnioinfusions for pregnant women facing early pregnancy renal anhydramnios, a condition that can be tough for the baby, to see if adding fluid to the amniotic sac can help keep both mom and baby healthy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10799564 on NIH RePORTER |
What this research studies
This research investigates the use of serial amnioinfusions as a treatment for early pregnancy renal anhydramnios (EPRA), a condition that can lead to severe complications for the fetus. The study aims to assess the safety and effectiveness of this novel therapy, which involves introducing fluid into the amniotic sac to support fetal development. By conducting a multi-center trial, the researchers will gather data on both maternal and fetal outcomes, providing insights into the potential benefits of this approach for affected families.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant individuals diagnosed with early pregnancy renal anhydramnios.
Not a fit: Patients who are not pregnant or those whose fetuses do not have renal anhydramnios will not benefit from this research.
Why it matters
Potential benefit: If successful, this research could improve survival rates and respiratory function for fetuses diagnosed with renal anhydramnios.
How similar studies have performed: Preliminary case reports suggest that similar approaches have shown promise, but this study aims to provide systematic evidence for the first time.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Atkinson, Meredith Ann — Johns Hopkins University
- Study coordinator: Atkinson, Meredith Ann
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.