Evaluating a new treatment for children with short bowel syndrome who rely on intravenous nutrition
A 90 day, Phase 3, Open Labeled Exploratory Study of RELiZORB to Evaluate Safety, Tolerability, and Nutrient Absorption in Children with Short Bowel Syndrome who are Dependent on Parenteral Nutrition
This study is looking at how well a special device called RELiZORB helps kids with short bowel syndrome absorb nutrients better, so they might be able to rely less on intravenous feeding and stay healthier.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Children's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10485212 on NIH RePORTER |
What this research studies
This research investigates the safety and effectiveness of RELiZORB, a device designed to improve nutrient absorption in children suffering from short bowel syndrome (SBS) who depend on parenteral nutrition (PN). The study will involve children who have difficulty absorbing nutrients due to a reduced length of small intestine. By using RELiZORB, the research aims to enhance the digestion of fats and essential fatty acids, potentially allowing these children to transition away from PN and reduce the risk of serious complications associated with long-term intravenous feeding.
Who could benefit from this research
Good fit: Ideal candidates for this research are children diagnosed with short bowel syndrome who are currently reliant on parenteral nutrition for their dietary needs.
Not a fit: Patients who do not have short bowel syndrome or those who are not dependent on parenteral nutrition may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the nutritional status and overall health of children with short bowel syndrome, reducing their dependence on parenteral nutrition.
How similar studies have performed: Previous research has shown promise in improving nutrient absorption in similar patient populations, indicating that this approach may be effective.
Where this research is happening
Boston, United States
- Boston Children's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Puder, Mark — Boston Children's Hospital
- Study coordinator: Puder, Mark
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.