Evaluating a new scale to measure symptoms of chronic heart failure.
Official title: Psychometric Analyses and Quantitative Study Report for Qualification of the Chronic Heart Failure Symptom Scale (CHF-SS) (DDT COA #000112)
Funded at Critical Path Institute · NIH-11087976 · Data updated 2026-11-12
This study is working on a new tool to help understand the symptoms of chronic heart failure, like breathlessness and fatigue, and it’s looking for patients to share their experiences so we can make sure it’s really helpful for improving treatment.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Critical Path Institute NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project start | September 1, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $249,826 |
| NIH project number | 1U01FD008423-01 |
| Project ID | NIH-11087976 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with chronic heart failure who experience significant symptoms affecting their daily lives.
✕Less likely to help
Patients without a diagnosis of chronic heart failure or those with mild symptoms may not benefit from this research.
What this research studies
This research focuses on developing and validating a new tool, the Chronic Heart Failure Symptom Scale (CHF-SS), to better assess the symptoms experienced by patients with chronic heart failure. The study aims to gather quantitative evidence to support the qualification of this scale for use in drug development, ensuring it meets the latest FDA guidelines. By analyzing the severity of symptoms like breathlessness, fatigue, and swelling, the research seeks to improve how heart failure is evaluated and treated. Patients may be asked to provide feedback on their symptoms to help refine this new measurement tool.
Why it matters
Potential benefit: If successful, this research could lead to more accurate assessments of heart failure symptoms, ultimately improving treatment options and patient outcomes.
How similar studies have gone: Previous research has shown success in developing patient-reported outcome measures for chronic conditions, indicating a promising approach for this new scale.
Where this research is happening
-
Critical Path Institute
Tucson, United States Active
Researchers
- Principal investigator: Mattera, Maria — Critical Path Institute
- Study coordinator: Mattera, Maria
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.