Evaluating a new method to safely rule out pulmonary embolism in children without using radiation
BEdside Exclusion of Pulmonary Embolism in children without Radiation (BEEPER)
This study is testing a new way to help doctors figure out if kids aged 5-17 might have a blood clot in their lungs, called pulmonary embolism, so they can avoid unnecessary scans and still make sure those who need treatment get it quickly.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wayne State University NIH-funded |
| Lab location | 1 site (Detroit, United States) |
| Project ID | NIH-10841548 on NIH RePORTER |
What this research studies
This research investigates a new approach called PERC-Peds, which modifies existing criteria used in adults to help doctors determine if children aged 5-17 may have pulmonary embolism (PE). The study aims to collect data on the symptoms and health conditions of children suspected of having PE in emergency departments. By using this method, the researchers hope to reduce unnecessary radiation exposure from CT scans while ensuring that children who truly have PE are diagnosed promptly. The study will involve around 4,030 children and will track their health outcomes over 45 days to assess the effectiveness of this new approach.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 5-17 who present with symptoms that raise suspicion for pulmonary embolism in emergency departments.
Not a fit: Patients outside the age range of 5-17 years or those without symptoms suggestive of pulmonary embolism may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly reduce the number of unnecessary CT scans in children, lowering their risk of radiation exposure while ensuring timely diagnosis of pulmonary embolism.
How similar studies have performed: While the approach of modifying existing adult criteria for children is innovative, similar methodologies have shown promise in other areas of pediatric care, suggesting potential for success.
Where this research is happening
Detroit, United States
- Wayne State University — Detroit, United States (Active)
Researchers
- Principal investigator: Kline, Jeffrey a — Wayne State University
- Study coordinator: Kline, Jeffrey a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.