Evaluating a new injectable contraceptive for women
CCTN - PHARMACOKINETIC AND PHARMACODYNAMIC EVALUATION OF LEVONORGESTREL BUTANOATE FOR FEMALE CONTRACEPTION - COLOMBIA
This study is testing a new long-lasting birth control shot called levonorgestrel butanoate, which is made especially for women, especially those who are overweight, to help prevent blood clots while providing an easy-to-use alternative to daily pills.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia University Health Sciences NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11041809 on NIH RePORTER |
What this research studies
This research investigates a new long-acting injectable contraceptive formulation called levonorgestrel butanoate (LB), specifically designed for women, particularly those who are obese. The study aims to provide an estrogen-free option to reduce the risk of venous thromboembolism (VTE), which is a significant concern for this population. Participants will be involved in a clinical trial to assess the pharmacokinetics and pharmacodynamics of LB, ensuring its efficacy and safety as a contraceptive method. The trial will focus on ease of use compared to traditional contraceptive methods that require daily adherence.
Who could benefit from this research
Good fit: Ideal candidates for this research are women, particularly those who are obese and seeking effective contraception without the risks associated with estrogen.
Not a fit: Patients who are not seeking contraception or those who do not have concerns related to VTE may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a safer and more convenient contraceptive option for women, especially those at risk of VTE.
How similar studies have performed: Previous research has shown success with other long-acting contraceptive methods, indicating potential for this novel approach.
Where this research is happening
New York, United States
- Columbia University Health Sciences — New York, United States (Active)
Researchers
- Principal investigator: Westhoff, Carolyn L — Columbia University Health Sciences
- Study coordinator: Westhoff, Carolyn L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.