Evaluating a new cervical cancer screening method for women living with HIV
COMParative ASSessment of p16/Ki-67 DUal Staining Technology in women living with HIV (COMPASS-DUST study)
This study is testing a new way to check for cervical cancer using a special staining method called p16/Ki-67 in women with HIV, and by joining in, you can help improve how we screen for this cancer in sub-Saharan Africa, leading to earlier detection and better health outcomes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | College of Medicine, University of Lagos NIH-funded |
| Lab location | 1 site (Lagos, Nigeria) |
| Project ID | NIH-10865079 on NIH RePORTER |
What this research studies
This research focuses on assessing the effectiveness of a dual staining technology called p16/Ki-67 in screening for cervical cancer among women living with HIV. The study will involve comparing this new method with existing screening techniques to determine its accuracy and reliability. By participating, patients may contribute to improving cervical cancer screening practices in sub-Saharan Africa, which could lead to earlier detection and better outcomes. The research will be conducted by a team led by an experienced investigator from Nigeria, who aims to enhance clinical practices through rigorous evaluation.
Who could benefit from this research
Good fit: Ideal candidates for this research are women living with HIV who are at risk for cervical cancer.
Not a fit: Patients who are not living with HIV or who do not require cervical cancer screening may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate cervical cancer screenings for women living with HIV, potentially saving lives through earlier detection.
How similar studies have performed: This approach is novel in sub-Saharan Africa, but similar dual staining technologies have shown promise in other regions for improving cervical cancer screening accuracy.
Where this research is happening
Lagos, Nigeria
- College of Medicine, University of Lagos — Lagos, Nigeria (Active)
Researchers
- Principal investigator: Okunade, Kehinde Sharafadeen — College of Medicine, University of Lagos
- Study coordinator: Okunade, Kehinde Sharafadeen
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.