Evaluating a new approach for managing chest pain patients in outpatient settings

Testing a Cardiovascular Ambulatory Rapid Evaluation for Patients with Chest Pain (CARE-CP)

NIH-funded research Wake Forest University Health Sciences · NIH-11003318

This study is testing a new way to help people with chest pain who aren't at high risk by letting them go home from the emergency room instead of staying in the hospital, and then checking in with them within three days to make sure they're doing okay and to manage any heart health concerns.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionWake Forest University Health Sciences NIH-funded
Lab location1 site (Winston-Salem, United States)
Project IDNIH-11003318 on NIH RePORTER

What this research studies

This research investigates a new strategy called the Cardiovascular Ambulatory Rapid Evaluation (CARE) for patients experiencing chest pain. Instead of being hospitalized, moderate-risk patients will be discharged from the emergency department and receive follow-up care within 72 hours to manage cardiovascular risk factors and assess the need for further testing. The goal is to improve patient outcomes while reducing the strain on healthcare resources associated with unnecessary hospitalizations. By focusing on outpatient management, this approach aims to provide a more efficient and patient-centered care model.

Who could benefit from this research

Good fit: Ideal candidates for this research are moderate-risk patients who present with chest pain at emergency departments.

Not a fit: Patients with high-risk chest pain or those requiring immediate hospitalization may not benefit from this outpatient management approach.

Why it matters

Potential benefit: If successful, this research could lead to safer and more effective management of chest pain, reducing unnecessary hospitalizations and improving patient experiences.

How similar studies have performed: Preliminary data suggest that outpatient management for moderate-risk chest pain patients is promising, but this specific approach is still being evaluated for its effectiveness.

Where this research is happening

Winston-Salem, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.