Evaluating a combined approach to manage chronic pain
Pain Response Evaluation of a Combined Intervention to Cope Effectively (PRECICE)
This study is looking at whether taking duloxetine along with online therapy can help people with chronic pain feel better, and it includes some support to help you stick with the therapy; you'll be randomly placed in one of three groups to see which approach works best over six months.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wake Forest University Health Sciences NIH-funded |
| Lab location | 1 site (Winston-Salem, United States) |
| Project ID | NIH-9870024 on NIH RePORTER |
What this research studies
This research investigates the effectiveness of a combination therapy involving duloxetine and web-based cognitive behavioral therapy (CBT) for patients suffering from chronic musculoskeletal pain (CMP). The study aims to enhance treatment outcomes by incorporating motivational interviewing to support adherence to the CBT program. Participants will be randomly assigned to receive either the combination therapy with nurse support, combination therapy without support, or duloxetine alone over a 24-week period. The goal is to determine if the combined approach leads to better pain management compared to duloxetine alone.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults experiencing chronic musculoskeletal pain who are seeking new treatment options.
Not a fit: Patients who do not have chronic musculoskeletal pain or those who are already receiving effective treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide a more effective treatment option for patients with chronic musculoskeletal pain, potentially improving their quality of life.
How similar studies have performed: Previous research has shown promise in using combination therapies for chronic pain management, suggesting that this approach may yield beneficial results.
Where this research is happening
Winston-Salem, United States
- Wake Forest University Health Sciences — Winston-Salem, United States (Active)
Researchers
- Principal investigator: Ang, Dennis Chua — Wake Forest University Health Sciences
- Study coordinator: Ang, Dennis Chua
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.