Evaluating a collaborative care approach for treating substance use disorders
Official title: NIDA Clinical Trials Network: Big South/West Node - Revision - 18 KMD Co-Care
Funded at Ut Southwestern Medical Center · NIH-11292806 · Data updated 2026-11-12
This study is looking at how a team-based treatment plan can help adults struggling with substance use, especially with opioids and stimulants, by providing regular support and check-ins to see if it can reduce their substance use and improve their health over six months.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ut Southwestern Medical Center NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project start | March 1, 2025 |
| Project end | February 28, 2027 |
| Funding year | 2025 |
| Award (this year) | $5,606,566 |
| NIH project number | 3UG1DA020024-21S1 |
| Project ID | NIH-11292806 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults aged 21 and older who are experiencing moderate to severe substance use disorders involving opioids and/or stimulants.
✕Less likely to help
Patients with co-existing moderate to severe opioid use disorder may not benefit from this research.
What this research studies
This research investigates the effectiveness of a collaborative care intervention designed to help adults with moderate to severe substance use disorders, particularly those involving opioids and stimulants. Participants will receive a structured treatment plan that includes regular follow-ups and support from a team of healthcare providers. The study will assess how this approach impacts the frequency of substance use and overall health outcomes over a six-month period. By participating, patients may receive tailored support aimed at reducing their substance use and improving their quality of life.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for individuals struggling with substance use disorders, enhancing their recovery and overall well-being.
How similar studies have gone: Previous research has shown promising results for collaborative care approaches in managing substance use disorders, indicating potential for success in this study as well.
Where this research is happening
-
Ut Southwestern Medical Center
Dallas, United States Active
Researchers
- Principal investigator: Trivedi, Madhukar H. — Ut Southwestern Medical Center
- Study coordinator: Trivedi, Madhukar H.
Related research
Other NIH-funded projects on the same topics.
-
Developing targeted therapies for Ewing sarcoma
This study is working on new treatments for Ewing sarcoma, a cancer that mainly affects kids and teens, by finding ways to target a specific protein that helps the cancer grow, so that we can offer safer and better options for those fighting this disease.
-
Neural roots of how autistic adults understand word meaning
A study to understand how adults with autism process word meanings in the brain, aiming to improve language support.
-
A new approach to healing NF1-related tibia fractures in children
This grant aims to understand why some NF1-related leg fractures in kids don’t heal well and to develop better treatments to help them recover without complications.
-
Multi-center study on how ventilation during CPR relates to cardiac arrest outcomes
A large, real-world study will look at how ventilation during CPR affects survival after out-of-hospital cardiac arrest in adults.
-
National Spina Bifida Patient Registry across the U.S.
A national registry collects health information from people with spina bifida to help doctors and families get better, more consistent care.
-
MONA-LISA: Understanding Why Autoimmune Signals Turn into Lupus Over Time
A study using data and samples from people with early autoimmune signs to understand why some develop full-blown lupus and others do not.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.