Establishing a center for advanced electron diffraction technologies at UCLA
MEDIC - MicroED Imaging Center at UCLA
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-10862646
This study is working on improving a special imaging technique called cryo-electron microscopy to help scientists better understand tiny biological structures, which could lead to new treatments for patients like you.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-10862646 on ClinicalTrials.gov |
What this research studies
This research aims to create a national resource at UCLA focused on developing and disseminating advanced electron diffraction technologies, particularly cryo-electron microscopy (cryoEM). By overcoming challenges associated with traditional X-ray diffraction methods, this project seeks to enable the determination of macromolecular structures from very small crystals. Patients may benefit from the advancements in understanding complex biological structures, which could lead to new treatments and therapies. The research will involve training and collaboration to enhance the capabilities of researchers in this field.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with conditions that involve complex macromolecular structures, such as certain genetic disorders or diseases requiring targeted therapies.
Not a fit: Patients with conditions unrelated to macromolecular structures or those not requiring advanced structural biology techniques may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding protein structures, potentially resulting in new therapies for various diseases.
How similar studies have performed: Previous research has shown success with cryo-electron microscopy and microcrystal electron diffraction techniques, indicating a promising avenue for future advancements.
Where this research is happening
LOS ANGELES, UNITED STATES
- UNIVERSITY OF CALIFORNIA LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GONEN, TAMIR — UNIVERSITY OF CALIFORNIA LOS ANGELES
- Study coordinator: GONEN, TAMIR
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.