Environmental health across three generations in Northern Manhattan

CCCEH-3: Enhancing the impact of three generations of environmental health studies in NYC.

['FUNDING_OTHER'] · COLUMBIA UNIVERSITY HEALTH SCIENCES · NIH-11034431

Following mothers, their adult children, and grandchildren in Northern Manhattan to link local environmental exposures with health across generations.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorCOLUMBIA UNIVERSITY HEALTH SCIENCES (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-11034431 on ClinicalTrials.gov

What this research studies

If you join, we will keep in touch with you and family members who were part of Columbia’s long-running birth cohorts and invite new offspring to participate. We collect information about your home environment and health, and may ask for clinic visits, questionnaires, physical measurements, and biological samples such as blood. The team works closely with local community partners and youth groups and builds connections with other long-term cohorts to compare findings. The goal is to understand how exposures before birth, in childhood, and across generations relate to health as people age.

Who could benefit from this research

Good fit: Ideal participants are people from the original Columbia mothers-and-newborns cohorts, their adult children (now mostly late teens to mid-20s), and any grandchildren or offspring who live in or near Northern Manhattan and can share health information and samples.

Not a fit: People without ties to the cohorts or who cannot provide follow-up information, attend visits, or give samples are unlikely to be eligible or to benefit directly from this project.

Why it matters

Potential benefit: Could help reveal how environmental exposures across generations affect long-term health and guide prevention and care for families in affected communities.

How similar studies have performed: Long-term birth cohort studies have linked early-life exposures to later health outcomes, but following three generations together is less common and offers new insights.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.