Environmental drivers of toxic algal blooms and shellfish toxin risk

Project 2: Environmental forcing of harmful algal blooms and toxicity exposure

NIH-funded research Woods Hole Oceanographic Institution · NIH-11360099

Researchers are building models to predict when toxic algae will bloom and how people who eat shellfish or live near the coast might be exposed to toxins.

Quick facts

Grant typeP01 program project
Study typeNIH-funded research
Funding institutionWoods Hole Oceanographic Institution NIH-funded
Lab location1 site (Woods Hole, United States)
Project IDNIH-11360099 on NIH RePORTER

What this research studies

Researchers will combine ocean observations, lab studies of toxin-producing algae (Alexandrium catenella and Pseudo-nitzschia), and computer models to understand bloom timing and toxicity. They will update an Alexandrium model, develop a Pseudo-nitzschia model, and run hindcast simulations for the Gulf of Maine, comparing results to shellfish toxin measurements and other observations. A submodel will estimate human exposure to saxitoxin and domoic acid and models will be refined iteratively until they match real-world data before being used to forecast future events. The team will also apply and test their approach in Nauset Marsh and coastal Arctic settings to see how regional conditions change risks.

Who could benefit from this research

Good fit: Ideal candidates include people who harvest or frequently eat shellfish, live in affected coastal regions, or participate in community shellfish monitoring programs.

Not a fit: People with health concerns unrelated to seafood toxin exposure or those living far from coastal shellfish areas may not directly benefit.

Why it matters

Potential benefit: If successful, this work could give communities earlier warnings about toxic shellfish and help prevent poisonings.

How similar studies have performed: Prior monitoring and forecasting efforts have helped reduce some toxin exposures, and this project builds on that work with newer, region-specific models and expanded testing.

Where this research is happening

Woods Hole, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.