Enhancing pain management for patients undergoing thoracic surgery
Official title: Improving Analgesic Effectiveness and Safety with Proactive Precision Pain Management in Thoracic Surgical Patients with Lung Lesions
Funded at Opalgenix, INC. · NIH-10695275 · Data updated 2026-11-12
This study is looking to make pain relief better for people having chest surgeries by creating a personalized plan that considers each person's unique needs, helping to reduce the use of strong pain medications and improve recovery.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Opalgenix, INC. NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $644,425 |
| NIH project number | 1R43HL167661-01A1 |
| Project ID | NIH-10695275 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients scheduled for thoracic surgeries who are at risk for severe postoperative pain and chronic pain development.
✕Less likely to help
Patients who are not undergoing thoracic surgery or those with pre-existing chronic pain conditions unrelated to surgical intervention may not benefit from this research.
What this research studies
This research focuses on improving pain management for patients undergoing thoracic surgeries, such as pneumonectomy and lobectomy, which are often associated with severe pain and high opioid use. The study aims to develop a proactive, precision pain management approach that tailors pain relief strategies based on individual patient characteristics, including genetic factors. By utilizing predictive algorithms, the research seeks to identify patients at risk for chronic pain and optimize their postoperative recovery experience. This personalized approach aims to minimize opioid use and improve overall safety outcomes for patients.
Why it matters
Potential benefit: If successful, this research could lead to more effective pain management strategies, reducing the risk of chronic pain and opioid dependency for thoracic surgery patients.
How similar studies have gone: Previous research has shown promise in using personalized pain management approaches, indicating that this method could lead to significant improvements in patient outcomes.
Where this research is happening
-
Opalgenix, INC.
Indianapolis, United States Active
Researchers
- Principal investigator: Plump, Steven R. — Opalgenix, INC.
- Study coordinator: Plump, Steven R.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.