Enhancing brain recovery using modified sugars
Improving Brain Recovery Through Glycoengineering
This study is looking at how special sugars can help the brain heal better after injuries by changing how brain cells work together, and it's for anyone interested in new ways to improve recovery from brain damage.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10907045 on NIH RePORTER |
What this research studies
This research investigates how modified sugars can improve brain recovery after injuries by altering the way brain cells interact and function. The approach involves using non-natural sugars that change the chemical properties of cell surfaces, which can influence cell behavior such as adhesion and growth. By studying these modified sugars in human neural stem cells, the researchers aim to understand their effects on brain cell differentiation and recovery processes. The ultimate goal is to develop new treatments that enhance brain healing and function following injury.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who have suffered from acquired brain injuries and are seeking new treatment options.
Not a fit: Patients with chronic or irreversible brain damage may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to innovative therapies that significantly improve recovery outcomes for patients with brain injuries.
How similar studies have performed: Previous research has shown promising results using similar glycoengineering approaches, indicating potential for success in this novel application.
Where this research is happening
Baltimore, United States
- University of Maryland Baltimore — Baltimore, United States (Active)
Researchers
- Principal investigator: Jia, Xiaofeng — University of Maryland Baltimore
- Study coordinator: Jia, Xiaofeng
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.