Enhancing brain imaging techniques for better diagnosis and treatment planning

Improving the sensitivity and specificity of diffusion MRI

['FUNDING_R01'] · VANDERBILT UNIVERSITY · NIH-11134203

This study is working on making brain scans even better at showing how brain fibers connect and how healthy the tissue is, which can help doctors detect strokes and plan surgeries, so patients can get clearer and more reliable information about their brain without any invasive procedures.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorVANDERBILT UNIVERSITY (nih funded)
Locations1 site (Nashville, UNITED STATES)
Trial IDNIH-11134203 on ClinicalTrials.gov

What this research studies

This research focuses on improving diffusion magnetic resonance imaging (DMRI) to better detect brain fiber pathways and assess tissue microstructure. By developing advanced algorithms, the project aims to enhance the accuracy and reliability of DMRI analysis, which is crucial for applications like stroke detection and surgical planning. Patients will benefit from noninvasive imaging methods that provide detailed insights into their brain's structure and connectivity. The research will validate these new methods to ensure they can be effectively used in clinical settings.

Who could benefit from this research

Good fit: Ideal candidates for this research include adults over 21 years old who have experienced acquired brain injuries or other neurological conditions.

Not a fit: Patients with conditions unrelated to brain structure or connectivity may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more accurate diagnoses and better treatment planning for patients with brain injuries or conditions.

How similar studies have performed: Previous research has shown promising results in improving imaging techniques, suggesting that this approach could lead to significant advancements in brain imaging.

Where this research is happening

Nashville, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired brain injury

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.