Energize-MBC: a web-based fatigue program for women with metastatic breast cancer
Adaptation and Preliminary Evaluation of Energize-MBC: Cognitive Behavioral Therapy for Fatigue among Women with Metastatic Breast Cancer
This project will adapt a cognitive behavioral therapy program delivered online to help women with metastatic breast cancer who have tiring side effects from CDK4/6 inhibitor treatment.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | H. Lee Moffitt Cancer Ctr & Res Inst NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project ID | NIH-11194344 on NIH RePORTER |
What this research studies
If you join, you would use a web-based version of cognitive behavioral therapy tailored for people living with metastatic breast cancer and treatment-related fatigue. The team will refine the online platform, deliver sessions by telemedicine, and may include wearable activity tracking to monitor daily movement and sleep. The pilot will focus on whether the program is acceptable and workable for participants and will collect early signals about changes in fatigue and daily functioning. Feedback from participants will be used to finalize the program for a larger future trial.
Who could benefit from this research
Good fit: Women living with metastatic breast cancer who are receiving or recently received a CDK4/6 inhibitor and who are experiencing bothersome fatigue are the intended participants.
Not a fit: People without metastatic breast cancer, not taking CDK4/6 inhibitors, or those who are medically unstable or unable to use telemedicine likely would not benefit or be eligible.
Why it matters
Potential benefit: If successful, the program could reduce treatment-related fatigue and help people feel more able to do daily activities.
How similar studies have performed: Cognitive behavioral therapy for fatigue has shown large benefits in people treated for curable cancers, but it has not been specifically tested in women with metastatic breast cancer on CDK4/6 inhibitors.
Where this research is happening
Tampa, United States
- H. Lee Moffitt Cancer Ctr & Res Inst — Tampa, United States (Active)
Researchers
- Principal investigator: Jim, Heather S.l. — H. Lee Moffitt Cancer Ctr & Res Inst
- Study coordinator: Jim, Heather S.l.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.