NIH-funded research R01 grant

ENDS and tobacco policy: how policy choices affect tobacco-related harms

Official title: The Interplay of ENDS and Tobacco Control Policy: Impact on the Population Harms of Tobacco

Funded at Healthpartners Institute · NIH-11365175 · Data updated 2026-11-12

This project looks at how electronic nicotine delivery systems (ENDS) and different tobacco policies shape the overall harms from tobacco for the population.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionHealthpartners Institute
NIH-funded
Lab location1 site (Bloomington, UNITED STATES)
Project startJuly 1, 2022
Project endJune 30, 2027
Funding year2026
Award (this year)$345,636
NIH project number5R01CA263542-05
Project IDNIH-11365175 on NIH RePORTER

Who could benefit from this research

Could help

Not applicable; this is a population and policy-focused project rather than a patient-specific trial.

Less likely to help

There is no direct patient participation expected in this model-based study.

What this research studies

If funded, researchers will use simulations to explore how stronger policies (like higher taxes, more tobacco-control spending, and stricter indoor bans) interact with ENDS to either reduce or shift tobacco-related harms. The study aims to understand how ENDS could help or hinder public health depending on the policy environment, and it will consider different scenarios to inform policy decisions. The focus is on populations and policy outcomes, not on treating individual patients. The work could inform better, evidence-based approaches to reduce tobacco-caused disease at a community or national level.

Why it matters

Potential benefit: If successful, the findings could guide policymakers on optimizing tobacco control to maximize population health.

How similar studies have gone: Previous simulations have shown that policy intensity can influence tobacco-related harms, but results vary with policy context and ENDS use.

Where this research is happening

  • Healthpartners Institute
    Bloomington, United States
    Active

Researchers

  • Principal investigator: Maciosek, Michael V — Healthpartners Institute
  • Study coordinator: Maciosek, Michael V

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.