Ending HIV in mothers, babies, children, and teens
IMPAACT Leadership Group
Testing safer, longer-lasting HIV and TB treatments and ways to control HIV without daily pills for pregnant people, infants, children, and adolescents.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-11457798 on NIH RePORTER |
What this research studies
This program runs clinical trials around the world that focus on pregnant and postpartum people, infants, children, and adolescents affected by HIV. You might be invited to join studies that try new drug doses, longer-acting medications, TB prevention and treatment approaches, or strategies aimed at controlling HIV after stopping daily therapy. Participants typically have health checks, blood tests, drug level monitoring, and follow-up visits to track safety and how well treatments work. Some studies collect samples for future lab work and include special visits for pregnant people and newborns to protect both mother and baby.
Who could benefit from this research
Good fit: People who are pregnant or postpartum with HIV, infants, children, adolescents living with HIV, and caregivers connected to those groups are the most likely candidates for specific trials.
Not a fit: People without HIV or those excluded by age limits, medical conditions, or specific trial eligibility rules are unlikely to receive direct benefit from these studies.
Why it matters
Potential benefit: If successful, the work could produce safer dosing, longer-acting HIV medicines, better TB care, and approaches that reduce or eliminate the need for daily antiretroviral pills for these groups.
How similar studies have performed: Prior IMPAACT trials and other pediatric/adolescent HIV studies have led to approved drugs and improved dosing, though ART-free remission approaches are still largely experimental.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Nachman, Sharon a — Johns Hopkins University
- Study coordinator: Nachman, Sharon a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.