Encouraging more frequent HIV retesting for adults at higher risk

Transformative approaches to rapidly and efficiently test demand creation interventions to promote HIV retesting in adults at increased risk of HIV

['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-11145109

This project tries out small, low-cost behavioral nudges to help adults at higher risk of HIV get retested more often.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded)
Locations1 site (SAN FRANCISCO, UNITED STATES)
Trial IDNIH-11145109 on ClinicalTrials.gov

What this research studies

The research team will work with community members to adapt simple reminders, prompts, and incentives that address common reasons people skip retesting. They will prototype these nudges with end users and local partners to make sure they fit the local context. Then participants at multiple clinic sites in sub-Saharan Africa will be randomly offered different nudges so researchers can see which approaches lead to more retesting. The study tracks return testing, linkage to care, and uptake of prevention like PrEP to identify practical strategies clinics can use.

Who could benefit from this research

Good fit: Adults (age 21+) at increased risk of HIV—such as people with recent exposures, partners with HIV, or those eligible for PrEP—who live near participating clinics in sub-Saharan Africa.

Not a fit: Children and adolescents under 21, people not at increased risk, or those already on continuous testing schedules or fully engaged in care may not receive direct benefit from this project.

Why it matters

Potential benefit: If successful, this could lead to more timely HIV diagnoses and increase linkage to treatment or prevention services like PrEP.

How similar studies have performed: Related low-cost behavioral 'nudge' approaches have improved health behaviors in other areas, but large-scale evidence specifically showing increased HIV retesting is still limited.

Where this research is happening

SAN FRANCISCO, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.