Empilisweni Initiative — Making cervical cancer screening and same-day treatment easier to get

The Empilisweni Initiative - Advancing Implementation of Cervical Cancer Control

NIH-funded research Columbia University Health Sciences · NIH-11404748

This project aims to bring HPV screening and same-day treatment to people at risk of cervical cancer in South Africa and similar communities.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11404748 on NIH RePORTER

What this research studies

If I live in a participating community, the project will help local clinics offer HPV-based screening and immediate treatment for pre-cancerous changes. Researchers from Columbia and the University of Cape Town will adapt proven screen-and-treat methods, train clinic staff, and work with community partners to make services practical and affordable. They will collect information on who gets screened and treated, how well the approach works in real clinics, and what it costs. The work builds on decades of research in Khayelitsha and follows WHO guidance to scale up prevention in low- and middle-income settings.

Who could benefit from this research

Good fit: People with a cervix who are eligible for cervical cancer screening at participating clinics—typically adolescents and adults in recommended screening age ranges—are the intended candidates.

Not a fit: People outside the project areas, those not eligible for screening by age or guidelines, or those already needing advanced cancer treatment may not get direct benefit from this initiative.

Why it matters

Potential benefit: If successful, more people could get timely screening and same-day treatment, preventing cancers and saving lives.

How similar studies have performed: Previous trials from the Khayelitsha program and other studies have shown HPV-based screen-and-treat is safe and effective, though broader implementation in routine care remains limited.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Cancer CauseCancer ControlCancer Control ScienceCancer EtiologyCervical Cancer
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.