Electrografted-MoS2 Immunosensor for Biomarker Detection
Official title: Electrografted-MoS2 Immunosensor
Funded at Southern Illinois University Carbondale · NIH-11444942 · Data updated 2026-11-12
A university-led project is developing a robust, covalently linked antibody–MoS2 biosensor to detect biomedical markers.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Southern Illinois University Carbondale NIH-funded |
| Lab location | 1 site (Carbondale, United States) |
| Project start | September 1, 2026 |
| Project end | August 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $556,875 |
| NIH project number | 1R15EB040449-01 |
| Project ID | NIH-11444942 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are individuals whose diseases are monitored by the specific biomarkers targeted by the sensor, or patients who could benefit from improved point-of-care diagnostics.
✕Less likely to help
Patients whose biomarker profile is not compatible with the sensor’s target could receive no direct benefit.
What this research studies
This project explores a new immunosensing interface that uses a covalently attached antibody on a two-dimensional MoS2 surface to improve stability and sensitivity. It will characterize the materials and methods to create a solid-state, covalently bonded sensor and test its performance. Undergraduate researchers will gain hands-on experience in materials science, surface chemistry, and biosensor testing to advance a promising diagnostic approach.
Why it matters
Potential benefit: If successful, the sensor could enable more reliable and cost-effective diagnostic tools for detecting disease biomarkers.
How similar studies have gone: Previous MoS2-based sensors have shown promise, but covalently tethered interfaces remain an area with limited demonstrated clinical performance.
Where this research is happening
-
Southern Illinois University Carbondale
Carbondale, United States Active
Researchers
- Principal investigator: Shamsi, Mohtashim H — Southern Illinois University Carbondale
- Study coordinator: Shamsi, Mohtashim H
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.