Electrical and ultrasound markers for myofascial pain

Electrophysiological and ultrasound quantitative biomarkers for myofascial pain

NIH-funded research Beth Israel Deaconess Medical Center · NIH-11363198

This project will use painless electrical and ultrasound measurements to find clear signs of myofascial pain in adults.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBeth Israel Deaconess Medical Center NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-11363198 on NIH RePORTER

What this research studies

You would receive non-invasive tests that use tiny electrical currents and ultrasound imaging to look for changes in muscles and trigger points linked to myofascial pain. The team will use electrical impedance myography, myofiber threshold-tracking excitability testing, and ultrasound measures — two of these methods are new to this condition. Many of the tests are painless and quick, and one technique (electrical impedance myography) can even be performed outside the clinic. The goal is to better identify active vs latent trigger points and to track how those findings change after common treatments like injections, dry needling, or myofascial release.

Who could benefit from this research

Good fit: Adults with localized or chronic myofascial pain and identifiable trigger points would be the most suitable candidates for participation.

Not a fit: People without myofascial pain (for example those with purely neuropathic pain, systemic pain syndromes, or anyone under age 21) are unlikely to gain direct benefit from this project.

Why it matters

Potential benefit: If successful, this work could give doctors clearer, objective ways to diagnose myofascial pain and to see whether treatments are working.

How similar studies have performed: Electrical impedance myography has shown useful signals in other muscle conditions, but combining EIM with threshold-tracking excitability testing and ultrasound for myofascial pain is largely novel.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.