Effects of wildfire smoke on heart health and iron balance

Impact of Biomass Burning Aerosol and Humic-like Substances on Iron Homeostasis and Atherosclerosis

NIH-funded research University of California Los Angeles · NIH-10906216

This study is looking at how breathing in smoke from wildfires might affect your heart health and iron levels, helping us understand the unique risks of wildfire smoke compared to city air pollution.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles NIH-funded
Lab location1 site (Los Angeles, United States)
Project IDNIH-10906216 on NIH RePORTER

What this research studies

This research investigates how exposure to biomass burning aerosols from wildfires affects heart health and iron levels in the body. It focuses on understanding the cardiovascular effects of these aerosols, which may differ from urban air pollution. The study will use laboratory-generated aerosols and controlled inhalation exposures to assess their impact on inflammation and atherosclerosis, a condition characterized by the buildup of fatty deposits in arteries. By examining these effects, the research aims to uncover new insights into the health risks associated with wildfire smoke.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with a history of cardiovascular issues or those living in areas frequently affected by wildfires.

Not a fit: Patients who do not have cardiovascular conditions or are not exposed to wildfire smoke may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and prevention strategies for cardiovascular diseases linked to air pollution from wildfires.

How similar studies have performed: While there is existing research on urban air pollution and cardiovascular health, this specific focus on biomass burning aerosols is novel and has not been extensively studied.

Where this research is happening

Los Angeles, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.