Effects of using both e-cigarettes and traditional cigarettes on heart health

Cardiovascular Effects of Inhalable Tobacco Product Dual Use

['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · NIH-10946632

This study looks at how using both e-cigarettes and regular cigarettes together can affect your heart and blood vessels, helping us understand the risks so we can better inform people about the dangers of using both types of tobacco.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA, SAN FRANCISCO (nih funded)
Locations1 site (SAN FRANCISCO, UNITED STATES)
Trial IDNIH-10946632 on ClinicalTrials.gov

What this research studies

This research investigates how the combined use of e-cigarettes and traditional cigarettes affects cardiovascular health. It examines the toxic effects of these inhalable tobacco products on blood vessels and heart function, utilizing both human and animal models. The study aims to identify the specific harmful components of these products and their impact on inflammation and vascular health. By understanding these effects, the research seeks to inform regulatory bodies about the risks associated with dual use of tobacco products.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who use both e-cigarettes and traditional cigarettes.

Not a fit: Patients who do not use any form of tobacco or have pre-existing severe cardiovascular conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and prevention of cardiovascular diseases linked to tobacco product use.

How similar studies have performed: Previous research has indicated that both e-cigarettes and traditional cigarettes can have harmful cardiovascular effects, suggesting that this study builds on established findings.

Where this research is happening

SAN FRANCISCO, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.