NIH-funded research R01 grant

Effects of using both e-cigarettes and traditional cigarettes on heart health

Official title: Cardiovascular Effects of Inhalable Tobacco Product Dual Use

Funded at University of California, San Francisco · NIH-10946632 · Data updated 2026-11-12

This study looks at how using both e-cigarettes and regular cigarettes together can affect your heart and blood vessels, helping us understand the risks so we can better inform people about the dangers of using both types of tobacco.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Francisco
NIH-funded
Lab location1 site (San Francisco, United States)
Project startSeptember 15, 2024
Project endJune 30, 2029
Funding year2024
Award (this year)$807,500
NIH project number1R01HL174690-01
Project IDNIH-10946632 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals who use both e-cigarettes and traditional cigarettes.

Less likely to help

Patients who do not use any form of tobacco or have pre-existing severe cardiovascular conditions may not benefit from this research.

What this research studies

This research investigates how the combined use of e-cigarettes and traditional cigarettes affects cardiovascular health. It examines the toxic effects of these inhalable tobacco products on blood vessels and heart function, utilizing both human and animal models. The study aims to identify the specific harmful components of these products and their impact on inflammation and vascular health. By understanding these effects, the research seeks to inform regulatory bodies about the risks associated with dual use of tobacco products.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and prevention of cardiovascular diseases linked to tobacco product use.

How similar studies have gone: Previous research has indicated that both e-cigarettes and traditional cigarettes can have harmful cardiovascular effects, suggesting that this study builds on established findings.

Where this research is happening

  • University of California, San Francisco
    San Francisco, United States
    Active

Researchers

  • Principal investigator: Springer, Matthew Lawrence — University of California, San Francisco
  • Study coordinator: Springer, Matthew Lawrence

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.