Effects of using both cigarettes and e-cigarettes on heart and lung health
Official title: Cardiopulmonary outcomes of dual cigarette and e-cigarette use in animal models of chronic exposure
Funded at Northeastern University · NIH-11088886 · Data updated 2026-11-12
This study is looking at how using both regular cigarettes and new pod-style e-cigarettes affects heart and lung health, and it's designed to help us understand if using both together is riskier than using just one of them.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northeastern University NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | May 18, 2023 |
| Project end | April 30, 2028 |
| Funding year | 2025 |
| Award (this year) | $770,680 |
| NIH project number | 5R01HL168719-03 |
| Project ID | NIH-11088886 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals over 21 years old who are current smokers or dual users of cigarettes and e-cigarettes.
✕Less likely to help
Patients who do not use tobacco products or e-cigarettes will not benefit from this research.
What this research studies
This research investigates the health impacts of using both traditional cigarettes and new pod-style e-cigarettes on the heart and lungs. By using animal models, specifically mice, the study will expose them to different combinations of cigarette smoke and e-cigarette aerosols to observe how these substances affect cardiovascular and respiratory systems. The goal is to understand whether dual use of these products leads to greater health risks compared to using either one alone. This research aims to provide critical data that could inform future regulations on e-cigarettes.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and regulations regarding the health risks associated with dual use of cigarettes and e-cigarettes.
How similar studies have gone: While the health impacts of traditional cigarette smoking are well-documented, the specific effects of dual use with e-cigarettes are still being explored, making this research a novel investigation.
Where this research is happening
-
Northeastern University
Boston, United States Active
Researchers
- Principal investigator: Bellini, Chiara — Northeastern University
- Study coordinator: Bellini, Chiara
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.