Effects of trichloroethylene on placental cells and pregnancy outcomes
Official title: Toxic effects of trichloroethylene and its metabolite on placental cells at the maternal-fetal interface
Funded at San Diego State University · NIH-10948862 · Data updated 2026-11-12
This study is looking at how the chemical trichloroethylene might impact the cells in the placenta during pregnancy, with the goal of finding ways to protect both moms and babies from potential health issues like low birth weight.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | San Diego State University NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project start | July 20, 2024 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $176,270 |
| NIH project number | 1K01ES036552-01 |
| Project ID | NIH-10948862 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include pregnant individuals who have been exposed to trichloroethylene or similar environmental contaminants.
✕Less likely to help
Patients who are not pregnant or have not been exposed to trichloroethylene may not benefit from this research.
What this research studies
This research investigates how exposure to the industrial solvent trichloroethylene affects placental cells, which play a crucial role in pregnancy. The study aims to understand the mechanisms by which this chemical may lead to adverse birth outcomes, such as low birth weight and restricted fetal growth. By utilizing advanced technologies and in vitro models, the research seeks to identify ways to mitigate these harmful effects. The findings could provide insights into improving maternal and fetal health.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention of adverse birth outcomes related to environmental exposures.
How similar studies have gone: Previous research has indicated that environmental contaminants can adversely affect pregnancy outcomes, suggesting that this study builds on established findings.
Where this research is happening
-
San Diego State University
San Diego, United States Active
Researchers
- Principal investigator: Elkin, Elana — San Diego State University
- Study coordinator: Elkin, Elana
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.