Effects of treating constipation in patients with chronic kidney disease
Clinical, Biochemical, and Microbiological Effects of Constipation Treatment in Patients with Chronic Kidney Disease: A Pilot Feasibility Trial
This study is looking at how treating constipation might help people with chronic kidney disease feel better and improve their overall health, by checking how laxatives can change gut health and other important health markers.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tennessee Health Sci Ctr NIH-funded |
| Lab location | 1 site (Memphis, United States) |
| Project ID | NIH-10906180 on NIH RePORTER |
What this research studies
This research investigates how treating constipation can impact patients with chronic kidney disease (CKD). It focuses on understanding the relationship between constipation and CKD outcomes, particularly how laxatives may improve gut health and overall clinical conditions. The study will assess changes in gut microbiota, biochemical markers, and clinical outcomes in CKD patients who receive constipation treatment. By exploring these connections, the research aims to provide insights into better management strategies for CKD patients.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with chronic kidney disease who also experience constipation.
Not a fit: Patients with chronic kidney disease who do not experience constipation or have other gastrointestinal disorders unrelated to constipation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved health outcomes for patients with chronic kidney disease by addressing constipation and its associated complications.
How similar studies have performed: While there have been experimental studies in animals showing positive outcomes from constipation treatment in CKD, this research is novel as it aims to evaluate these effects in human patients.
Where this research is happening
Memphis, United States
- University of Tennessee Health Sci Ctr — Memphis, United States (Active)
Researchers
- Principal investigator: Sumida, Keiichi — University of Tennessee Health Sci Ctr
- Study coordinator: Sumida, Keiichi
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.