NIH-funded research R01 grant

Effects of timed eating on blood sugar and cell function in people with metabolic syndrome

Official title: Impact of Time-Restricted Feeding (TRF) on Glucose Homeostasis and Mitochondrial Function in Patients with Metabolic Syndrome

Funded at University of California, San Diego · NIH-11058313 · Data updated 2026-11-12

This study is looking at how eating within certain hours of the day can affect blood sugar levels and energy production in people with metabolic syndrome, and it aims to find out if this eating schedule can help improve their health.

More Metabolic Syndrome research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego
NIH-funded
Lab location1 site (La Jolla, United States)
Project startSeptember 15, 2018
Project endMarch 31, 2030
Funding year2025
Award (this year)$852,151
NIH project number2R01DK118278-06A1
Project IDNIH-11058313 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adults diagnosed with metabolic syndrome, which includes conditions like obesity, high blood pressure, and insulin resistance.

Less likely to help

Patients who do not have metabolic syndrome or those with severe metabolic disorders may not benefit from this research.

What this research studies

This research investigates how time-restricted feeding (TRF) can influence glucose levels and mitochondrial function in individuals diagnosed with metabolic syndrome. Participants will be involved in a randomized controlled trial where they will follow a specific eating schedule to assess its impact on their metabolic health. The study aims to understand the relationship between meal timing and metabolic processes, potentially leading to new dietary recommendations. Patients will be monitored for changes in blood glucose regulation and overall metabolic function throughout the trial.

Why it matters

Potential benefit: If successful, this research could lead to improved dietary strategies for managing metabolic syndrome and related conditions.

How similar studies have gone: Previous studies have shown promising results with time-restricted feeding in improving metabolic health, suggesting that this approach may be effective.

Where this research is happening

  • University of California, San Diego
    La Jolla, United States
    Active

Researchers

  • Principal investigator: Taub, Pam Rajendran — University of California, San Diego
  • Study coordinator: Taub, Pam Rajendran

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.