Effects of timed eating on blood sugar and cell function in people with metabolic syndrome
Official title: Impact of Time-Restricted Feeding (TRF) on Glucose Homeostasis and Mitochondrial Function in Patients with Metabolic Syndrome
Funded at University of California, San Diego · NIH-11058313 · Data updated 2026-11-12
This study is looking at how eating within certain hours of the day can affect blood sugar levels and energy production in people with metabolic syndrome, and it aims to find out if this eating schedule can help improve their health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | September 15, 2018 |
| Project end | March 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $852,151 |
| NIH project number | 2R01DK118278-06A1 |
| Project ID | NIH-11058313 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults diagnosed with metabolic syndrome, which includes conditions like obesity, high blood pressure, and insulin resistance.
✕Less likely to help
Patients who do not have metabolic syndrome or those with severe metabolic disorders may not benefit from this research.
What this research studies
This research investigates how time-restricted feeding (TRF) can influence glucose levels and mitochondrial function in individuals diagnosed with metabolic syndrome. Participants will be involved in a randomized controlled trial where they will follow a specific eating schedule to assess its impact on their metabolic health. The study aims to understand the relationship between meal timing and metabolic processes, potentially leading to new dietary recommendations. Patients will be monitored for changes in blood glucose regulation and overall metabolic function throughout the trial.
Why it matters
Potential benefit: If successful, this research could lead to improved dietary strategies for managing metabolic syndrome and related conditions.
How similar studies have gone: Previous studies have shown promising results with time-restricted feeding in improving metabolic health, suggesting that this approach may be effective.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Taub, Pam Rajendran — University of California, San Diego
- Study coordinator: Taub, Pam Rajendran
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.