Effects of THC on signaling in the brain and blood
Impact of THC on Extracellular Vesicle Signaling
This study is looking at how THC from cannabis affects tiny particles in the body that carry important information, to help us understand how it interacts with other substances like nicotine and what that means for your health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project ID | NIH-10829411 on NIH RePORTER |
What this research studies
This research investigates how THC, the main psychoactive component of cannabis, affects signaling mechanisms in the brain and blood. It focuses on understanding the role of extracellular vesicles, which are small particles released by cells that can carry important biological information. By examining how THC influences these vesicles and their RNA content, the study aims to identify potential biomarkers related to THC use and its interaction with other substances like nicotine. This research could provide valuable insights into the effects of cannabis on the body and brain.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who use cannabis, particularly those who may also use nicotine.
Not a fit: Patients who do not use cannabis or nicotine may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding of cannabis effects and potential biomarkers for monitoring its use.
How similar studies have performed: Other research has shown promising results in understanding cannabinoid effects, but this specific approach to extracellular vesicle signaling is relatively novel.
Where this research is happening
Irvine, United States
- University of California-Irvine — Irvine, United States (Active)
Researchers
- Principal investigator: Fowler, Christie D — University of California-Irvine
- Study coordinator: Fowler, Christie D
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.