Effects of THC and CBD on memory processes

ERP studies of acute influences of THC and CBD on memory encoding and retrieval processes

NIH-funded research University of Colorado · NIH-11092161

This study is looking at how different amounts of THC and CBD in cannabis affect your memory, so if you use cannabis, you can help us understand if CBD helps reduce any memory problems caused by THC.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Colorado NIH-funded
Lab location1 site (Boulder, UNITED STATES)
Project IDNIH-11092161 on NIH RePORTER

What this research studies

This research investigates how different ratios of THC and CBD, two compounds found in cannabis, affect memory encoding and retrieval. Participants will engage in memory tasks while under the influence of various cannabis strains that differ in their THC and CBD content. The study aims to understand whether CBD can mitigate the negative effects of THC on memory. By using a naturalistic observational design, participants will perform the same memory tasks on days when they are intoxicated and not intoxicated, allowing for a direct comparison of effects.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults who use cannabis and are interested in understanding its effects on their cognitive functions.

Not a fit: Patients who do not use cannabis or have contraindications to cannabis use may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding of how cannabis affects memory, potentially guiding safer use and therapeutic applications.

How similar studies have performed: Previous research has shown varying effects of cannabinoids on cognitive functions, but this study aims to explore a novel approach by focusing on real-world cannabis strains and their specific cannabinoid ratios.

Where this research is happening

Boulder, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.